The Nigerian duo of Victor Moses and Joseph Yobo could be on the bench in Nigeria's Group C clash with Ethiopia in Rustenburg on Tuesday.
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Moses, 22, made his debut at the Africa Cup of Nations against Zambia but showed signs of still struggling with his hamstring.
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The Chelsea attacking winger played for 78 minutes in the game against Zambia before he was substituted for Brown Ideye and is yet to recover from the injury, according to head coach, Stephen Keshi.
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Captain of the Super Eagles, Yobo is also a huge doubt owing to an ankle injury after missing the 1-1 draw with Zambia in Nelspruit on Friday.
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'' Victor Moses is still under observation. He's been training but not at 100 percent right now. Same goes for Joseph Yobo who missed the last game '' Keshi said.