Manchester United will face Chelsea in a mouth- watering FA Cup quarter-final if both clubs progress through their respective fifth-round ties.
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First Chelsea must overcome Middlesbrough on 27 February with the winner taking on either United or Reading, who face each other on Monday.
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Elsewhere, if Oldham can defeat Everton then they will host Wigan Athletic.
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Premier League champions Manchester City host Barnsley, while Millwall are at home to Blackburn Rovers.
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Wigan boss Roberto Martinez, who had earlier seen his side comfortably defeat Huddersfield 4-1 ,was delighted with the draw and believes his side are capable of progressing.
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"It's a great tie," Martinez said.
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"Oldham have been magnificent and it's a game that is still open so we will follow that one with interest. Every game is a priority for us.
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"What's important as a football club is that you are capable of facing two competitions. I think two, three, four years ago, we never had the opportunity to have a pool of 16-17 players and now we have that strength."
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Chelsea, who are looking to win the competition for a fourth time in five years, secured their place in round five with a 4-0 fourth-round replay defeat of Brentford.