Bayern Munich will be without Franck Ribery for their Champions League encounter with Arsenal, the Bundesliga leaders said on Monday.
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The France international sprained his left ankle in his side's 3-2 defeat of Fortuna Dusseldorf on Saturday, the club said.
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It was not immediately clear whether Ribery would be out for a longer period.
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Dutch winger Arjen Robben, who was able to train on Monday after recvoering from a muscle strain, could now start in the Allianz Arena on Tuesday.
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Bayern will also be without midfielder Bastian Schweinsteiger and defender Jerome Boateng, who are both suspended. Brazilian midfielder Luiz Gustavo is set to start for Schweinsteiger.
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Bayern lead the last-16 tie 3-1 from the first leg in the Emirates Stadium.
That won't have so much effect on the players cause they already know they've qualified