Libertad, Once Caldas and Universidad Catolica will hope to produce improbable comebacks against Penarol, Santos and Velez Sarsfield, while Cerro Porteno host Jaguares after their quarter-final, first leg ended all square.
Source: Former champs out to complete the job (http://www.fifa.com/worldfootball/clubfootball/news/newsid=1436885.html?cid=rssfeed&att=)