One man was killed and 15 people were injured in an attack against a group of protesters by hundreds of supporters of ousted Islamist President Mohamed Morsi.
The protest occurred near Cairo University early on Tuesday morning, a state-run news Website said.
Al-Ahram Online said police fired tear gas to quell the violence and several cars in the area were destroyed or set on fire.
Police sources said hundreds of pro-Morsi supporters clashed with local residents, street vendors and others near Cairo University's main campus in Giza province, south of Cairo.
They said gunshots were fired and stones were thrown during the incident.
One person was killed and 20 were injured on Monday in clashes between Morsi supporters and opponents in central Cairo.
Some 100 have been killed since the army overthrew Morsi, elected last year, on July 3 after mass protests.
The Muslim Brotherhood said on the Facebook page of its Freedom and Justice Party, which Morsi headed before he was elected president in June 2012, that five were killed in Tuesday's clashes.
"Leaders of the military coup continue to terrorise the peaceful protesters in Egypt,'' the FJP said in a statement in English.
The Brotherhood accuses the army of orchestrating a coup that has exposed deep political divisions in the Arab world's most populous and influential nation.
The Punch