Former world champions Italy and Germany are among seven countries who could confirm their places in next year's World Cup soccer finals in Brazil when the qualifying tournament swings back into action after a three-month break.
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The Netherlands, three times finalists, could also qualify from Europe with wins on both Friday and Tuesday while Switzerland and Bosnia could go through if they win and other results go their way.
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The United States would seal the first qualifying place from the Concacaf region with victories in Costa Rica and at home to Mexico while Argentina can guarantee a trip to neighbouring Brazil if they beat Paraguay on Tuesday.
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The former world champions, who top the South American standings, could even qualify before they face the bottom-placed Paraguayans if results go their way when they have a rest day on Friday.
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With the opening match in Sao Paulo on June 12, just over nine months away, hosts Brazil and the four Asian qualifiers of Japan, Australia, Iran and South Korea are the only countries through so far.
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The seven nations who will join already-qualified Ivory Coast, Egypt and Algeria in the final African qualifying round will be known.
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The 10 teams will be paired up and play each other home and away to decide Africa's five qualifiers for Brazil.
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In Asia, Jordan and Uzbekistan, neither of whom have reached the finals before, will meet over two legs on Friday and Tuesday to decide who qualifies for a playoff against the eventual fifth-placed South American team for a World Cup place.