Dani Alves scored their first goal from long range, 20-year-old forward Sandro Ramirez hit a a hat-trick, while Munir El Haddadi, also 20, got two goals.
Lionel Messi was left out of the squad, while Andres Iniesta, Neymar and Luis Suarez were unused substitutes.
Juanfran hit a consolation for the visitors, who had held Luis Enrique’s La Liga side 0-0 in the first leg.
That tie was played earlier than scheduled to allow Barca to play in the Fifa Club World Cup in Japan, where the Spanish club enter at the semi-final stage on 17 December.
Support InfoStride News' Credible Journalism: Only credible journalism can guarantee a fair, accountable and transparent society, including democracy and government. It involves a lot of efforts and money. We need your support. Click here to Donate